Cefcapene pivoxil

Overview
Catalog #	bs-83742c-20-mg
Product Name	Cefcapene pivoxil
Specifications
Storage Buffer	Off-white to beige solid
Storage Condition	-20°C
Target
Product Information	Cefcapene pivoxil is a pivalate ester prodrug form of the third generation cephalosporin Cefcapene. Displays broad-spectrum antibacterial activity against both Gram-negative and -positive bacteria including S. aureus.1 Cefcapene pivoxil potently suppresses gasdermin D-mediated pyroptosis via targeting of the oligomerization interface I.2 Active in vivo in a mouse model of sepsis. Cefcapene pivoxil acts synergistically with another gasdermin D inhibitor, SCR-1481B1 (Cat #10-3971), and a PD-L1 antibody to significantly enhance the antitumor activity of anti-PD-L1 therapy.
Description	CAS Number: 147816-24-8 Chemical Name: 2,2-Dimethylpropanoyloxymethyl (6R,7R)-7-[[(Z)-2-(2-amino-1,3-thiazol-4-yl)pent-2-enoyl]amino]-3-(carbamoyloxymethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate·hydrate·hydrochloride Molecular Weight: 622.11 Formula: C23H29N5O8S2·HCl·H2O Solubility: DMSO (85 mg/ml) Physical Properties: Off-white to beige solid Purity: >98% by HPLC, NMR (conforms)