VU0810464
| Overview | |
| Catalog # | bs-83797c-5-mg |
| Product Name | VU0810464 |
| Specifications | |
| Storage Buffer | White solid |
| Storage Condition | -20°C |
| Target | |
| Product Information | VU0810464 is potent (Kir3.1/3.2; GIRK1/2 EC50 = 165 nM) activator of G protein-gated inwardly-rectifying potassium channels (Kir3; GIRK).1,2 Displays selectivity for Kir3.1/3.2 versus Kir3.1/3.4 as well as selectivity for neuronal versus cardiac Kir3 channels. VU0810464 reduced stress-induced hyperthermia but not anxiety-related behavior in mice. |
| Description | CAS Number: 2126040-21-7 Chemical Name: 2-(3-Chloro-4-fluorophenyl)-N-(2-cyclohexyl-5-methylpyrazol-3-yl)acetamide Molecular Weight: 349.83 Formula: C18H21ClFN3O Solubility: DMSO (>25 mg/ml) Physical Properties: White solid Purity: >98% by TLC (NMR Conforms) |
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