CID16020046

Overview
Catalog #	bs-83841c-5mg
Product Name	CID16020046
Specifications
Storage Buffer	White to off-white solid
Storage Condition	-20°C
Target
Product Information	CID16020046 is a selective GPR55 antagonist.1 In HEK293 cells expressing GPR55, the compound behaves as an antagonist on lysophosphatidylinositol (LPI)-mediated Ca2+ release but was inactive on cells expressing CB1 and CB2. It blocks LPI-induced migration of colon cancer cells.2 It displays protective effects against oxidized LDL-induced inflammation3, mitigates advanced glycation end products-induced chondrocyte activation4, and displays anti-inflammatory effects in various cells5,6. A useful tool for studying the role of GPR55 in cellular physiology.
Description	CAS Number: 834903-43-4 Chemical Name: 4-[4,6-Dihydro-4-(3-hydroxyphenyl)-3-(4-methylphenyl)-6-oxopyrrolo[3,4-c]pyrazol-5(1H)-yl]benzoic acid Molecular Weight: 425.44 Formula: C25H19N3O4 Solubility: DMSO (45 mg/ml) Physical Properties: White to off-white solid Purity: >98% by HPLC NMR (Conforms)