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Hemoglobin Beta/Delta Polyclonal Antibody

Applications

  • WB
  • ELISA

Reactivity

  • Human
Overview
Catalog # bs-8554R
Product Name Hemoglobin Beta/Delta Polyclonal Antibody
Applications WB, ELISA
Specificity Antibody has equal affinity for Human Hemoglobin Beta and Delta
Reactivity Human
Specifications
Conjugation Unconjugated
Host Rabbit
Source KLH conjugated synthetic peptide derived from human Hemoglobin beta
Immunogen Range 51-147/147
Clonality Polyclonal
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage Condition Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
Target
Gene ID 3043; 3045
Swiss Prot P68871; P02042
Subcellular location Cytoplasm, Secreted
Synonyms CD113t-C; beta-globin; Hemoglobin subunit beta; Hemoglobin beta chain; HBB; Hemoglobin subunit delta; HBD; Delta-globin; Hemoglobin delta chain
Background The delta (HBD) and beta (HBB) genes are normally expressed in the adult: two alpha chains plus two beta chains constitute HbA, which in normal adult life comprises about 97% of the total hemoglobin. Two alpha chains plus two delta chains constitute HbA-2, which with HbF comprises the remaining 3% of adult hemoglobin. Five beta-like globin genes are found within a 45 kb cluster on chromosome 11 in the following order: 5'-epsilon--Ggamma--Agamma--delta--beta-3'. Mutations in the delta-globin gene are associated with beta-thalassemia.
Application Dilution
WB 1:300-5000
ELISA 1:500-1000