Help

LRP130/LRPPRC Polyclonal Antibody, HRP Conjugated

Applications

  • WB
  • IHC-P

Reactivity

  • Rat

Predicted Reactivity

  • Human
  • Mouse
  • Horse
  • Chicken
  • Rabbit
Overview
Catalog # bs-8719R-HRP
Product Name LRP130/LRPPRC Polyclonal Antibody, HRP Conjugated
Applications
WB IHC-P
Reactivity Rat
Predicted Reactivity Human, Mouse, Horse, Chicken, Rabbit
Specifications
Conjugation HRP
Host Rabbit
Source KLH conjugated synthetic peptide derived from human LRP130
Clonality Polyclonal
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage Condition Store at -20C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Target
Synonyms LRPPRC; 130 kDa leucine-rich protein; GP130; Leucine-rich PPR-mot containing protein; LRP 130; LPPRC_HUMAN.
Background Leucine-rich protein (LRP130) is a cytoplasmic mRNA-binding protein likely to be involved in the processing of mitochondrial DNA transcripts. Defects in the LRPPRC gene that encodes LRP130 result in the French-Canadian type of Leigh syndrome, a severe neurological disorder characterized by lesions in the subcortical region of the brain. LRP130 also interacts with the low-affinity receptor for leukemia inhibitory factor to produce an intracelluar signal cascade.
Application Dilution
WB 1:300-5000
IHC-P 1:200-400

Frequently asked questions

Which applications is LRP130/LRPPRC Polyclonal Antibody, HRP Conjugated (bs-8719R-HRP) validated for, and at what dilution?

bs-8719R-HRP is validated for WB (1:300-5000); IHC-P (1:200-400). These are recommended starting dilutions; optimal dilutions should be determined by the end user.

Which species does LRP130/LRPPRC Polyclonal Antibody, HRP Conjugated (bs-8719R-HRP) react with?

Tested reactivity: Rat. Predicted reactivity (expected from sequence homology but not yet tested): Human, Mouse, Horse, Chicken, Rabbit.

How should bs-8719R-HRP be stored?

Store at -20C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. Storage buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

What immunogen was used to raise LRP130/LRPPRC Polyclonal Antibody, HRP Conjugated (bs-8719R-HRP)?

KLH conjugated synthetic peptide derived from human LRP130