IP3 Receptor Polyclonal Antibody, Cy3 Conjugated
Applications
Reactivity
| Overview | |
| Catalog # | bs-8869R-Cy3-100uL |
| Product Name | IP3 Receptor Polyclonal Antibody, Cy3 Conjugated |
| Applications |
FCM
|
| Reactivity | Human, Mouse, Rat |
| Specifications | |
| Conjugation | Cy3 |
| Host | Rabbit |
| Source | KLH conjugated synthetic peptide derived from human IP3 Receptor |
| Immunogen Range | 101-200/2758 |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1ug/ul |
| Purification | Purified by Protein A. |
| Storage Buffer | Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| Storage Condition | Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target | |
| Gene ID | 3708 |
| Swiss Prot | Q14643 |
| Subcellular location | Cytoplasm |
| Synonyms | ACV; CLA4; IP3R; IP3R1; SCA15; SCA16; SCA29; INSP3R1; PPP1R94; Inositol 1,4,5-trisphosphate receptor type 1; IP3 receptor isoform 1; IP3R 1; Type 1 inositol 1,4,5-trisphosphate receptor; Type 1 InsP3 receptor; ITPR1 |
| Background | Intracellular channel that mediates calcium release from the endoplasmic reticulum following stimulation by inositol 1,4,5-trisphosphate. Plays a role in ER stress-induced apoptosis. Cytoplasmic calcium released from the ER triggers apoptosis by the activation of CaM kinase II, eventually leading to the activation of downstream apoptosis pathways (By similarity). |
| Application Dilution | |
| FCM | 1:200 |
Frequently asked questions
Which applications is IP3 Receptor Polyclonal Antibody, Cy3 Conjugated (bs-8869R-Cy3) validated for, and at what dilution?
bs-8869R-Cy3 is validated for FCM (1:200). These are recommended starting dilutions; optimal dilutions should be determined by the end user.
Which species does IP3 Receptor Polyclonal Antibody, Cy3 Conjugated (bs-8869R-Cy3) react with?
Tested reactivity: Human, Mouse, Rat.
How should bs-8869R-Cy3 be stored?
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. Storage buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
What immunogen was used to raise IP3 Receptor Polyclonal Antibody, Cy3 Conjugated (bs-8869R-Cy3)?
KLH conjugated synthetic peptide derived from human IP3 Receptor Immunogen range: 101-200/2758.
What are the excitation and emission wavelengths of the Cy3 conjugate (bs-8869R-Cy3)?
Cy3 on bs-8869R-Cy3: excitation / emission 512,550nm/570,615nm.