DPP6 Polyclonal Antibody
Applications
Reactivity
Overview | |
Catalog # | bs-9010R |
Product Name | DPP6 Polyclonal Antibody |
Applications | WB, IHC-P, IF(IHC-P) |
Reactivity | Human, Mouse, Rat |
Specifications | |
Conjugation | Unconjugated |
Host | Rabbit |
Source | KLH conjugated synthetic peptide derived from human DPP6 |
Immunogen Range | 401-500/865 |
Clonality | Polyclonal |
Isotype | IgG |
Concentration | 1ug/ul |
Purification | Purified by Protein A. |
Storage Buffer | 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
Storage Condition | Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Target | |
Gene ID | 1804 |
Subcellular location | Extracellular |
Synonyms | Dipeptidyl aminopeptidase like protein 6; Dipeptidyl aminopeptidase related protein; Dipeptidyl peptidase 6; Dipeptidyl peptidase IV like protein; Dipeptidylpeptidase 6; Dipeptidylpeptidase VI; DPPX; DPP6_HUMAN. |
Background | DPP6 is a Type-II serine proteinase of the clan SC. The clan SC proteinases have a catalytic triad of Ser-Asp-His, and like other Serine proteinases, the active site serine is in a Gly-Xaa-Ser-Xaa -Gly orientation. DPP6 has an Asp instead of Ser in the catalytic site. DPP6 is a member of a broader family of dipeptidyl peptidases including DPP4, FAP/Seprase, DPP2, DPP8, DPP9, DPP10, which have differing substrate specificity and tissue localizations. The surface-bound DPP6 is a homodimer, and cleavage of in the stalk region releases a shed form of DPP6. The shed is the form found in serum. DPP6 has been found in highest abundance in the brain, but also in the kidney, liver and lung. |
Application Dilution | |
WB | 1:300-5000 |
IHC-P | 1:200-400 |
IF(IHC-P) | 1:50-200 |