PDZD6 Polyclonal Antibody, PE Conjugated
Applications
Reactivity
Predicted Reactivity
| Overview | |
| Catalog # | bs-9041R-PE-100uL |
| Product Name | PDZD6 Polyclonal Antibody, PE Conjugated |
| Applications |
WB
|
| Reactivity | Human |
| Predicted Reactivity | Mouse, Rat, Rabbit |
| Specifications | |
| Conjugation | PE |
| Host | Rabbit |
| Source | KLH conjugated synthetic peptide derived from human PDZD6 |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1ug/ul |
| Purification | Purified by Protein A. |
| Storage Buffer | Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Store at -20C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target | |
| Gene ID | 27152 |
| Swiss Prot | Q9ULD6 |
| Subcellular location | Cytoplasm, Cell membrane, Cytoskeleton |
| Synonyms | Protein inturned; Inturned planar cell polarity effector homolog; PDZ domain-containing protein 6; INTU; KIAA1284; PDZD6; PDZK6; INTU_HUMAN. |
| Background | Plays a key role in ciliogenesis and embryonic development. Regulator of cilia formation by controlling the organization of the apical actin cytoskeleton and the positioning of the basal bodies at the apical cell surface, which in turn is essential for the normal orientation of elongating ciliary microtubules. Plays a key role in definition of cell polarity via its role in ciliogenesis but not via conversion extension. Has an indirect effect on hedgehog signaling (By similarity). Proposed to function as core component of the CPLANE (ciliogenesis and planar polarity effectors) complex involved in the recruitment of peripheral IFT-A proteins to basal bodies (PubMed:27158779). |
| Application Dilution | |
| WB | 1:300-5000 |
Frequently asked questions
Which applications is PDZD6 Polyclonal Antibody, PE Conjugated (bs-9041R-PE) validated for, and at what dilution?
bs-9041R-PE is validated for WB (1:300-5000). These are recommended starting dilutions; optimal dilutions should be determined by the end user.
Which species does PDZD6 Polyclonal Antibody, PE Conjugated (bs-9041R-PE) react with?
Tested reactivity: Human. Predicted reactivity (expected from sequence homology but not yet tested): Mouse, Rat, Rabbit.
How should bs-9041R-PE be stored?
Store at -20C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. Storage buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
What immunogen was used to raise PDZD6 Polyclonal Antibody, PE Conjugated (bs-9041R-PE)?
KLH conjugated synthetic peptide derived from human PDZD6
What are the excitation and emission wavelengths of the PE conjugate (bs-9041R-PE)?
PE on bs-9041R-PE: excitation / emission 496,564nm/578nm.