DHFR Polyclonal Antibody, APC Conjugated
Applications
Reactivity
| Overview | |
| Catalog # | bs-9058R-APC |
| Product Name | DHFR Polyclonal Antibody, APC Conjugated |
| Applications |
IF
|
| Reactivity | Human, Mouse |
| Specifications | |
| Conjugation | APC |
| Host | Rabbit |
| Source | KLH conjugated synthetic peptide derived from human DHFR |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1ug/ul |
| Purification | Purified by Protein A. |
| Storage Buffer | Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Store at -20C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target | |
| Gene ID | 1719 |
| Swiss Prot | P00374 |
| Subcellular location | Cytoplasm |
| Synonyms | DHFR; DHFRP1; Dihydrofolate reductase; DYR; DYR_HUMAN; EC 1.5.1.3. |
| Background | DHFR catalyzes the NADPH-dependent reduction of dihydrofolate to tetrahydrofolate, and is a crucial enzyme for the synthesis of purines, pyrimidines and some amino acids. Inhibition of the activity of this enzyme leads to arrest of DNA synthesis and cell death. Gene expression of methotrexate (MTX)-resistant variants of DHFR in normal hematopoietic cells is a potential strategy to permit administration of larger doses of MTX by alleviating drug toxicity in normal cells and tissues that are drug sensitive. |
| Application Dilution | |
| IF | |
Frequently asked questions
Which applications is DHFR Polyclonal Antibody, APC Conjugated (bs-9058R-APC) validated for, and at what dilution?
bs-9058R-APC is validated for IF.
Which species does DHFR Polyclonal Antibody, APC Conjugated (bs-9058R-APC) react with?
Tested reactivity: Human, Mouse.
How should bs-9058R-APC be stored?
Store at -20C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. Storage buffer: Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
What immunogen was used to raise DHFR Polyclonal Antibody, APC Conjugated (bs-9058R-APC)?
KLH conjugated synthetic peptide derived from human DHFR