DHFR Polyclonal Antibody, Biotin Conjugated
Applications
Reactivity
| Overview | |
| Catalog # | bs-9058R-Biotin |
| Product Name | DHFR Polyclonal Antibody, Biotin Conjugated |
| Applications |
IHC-P
IHC-F
|
| Reactivity | Human, Mouse |
| Specifications | |
| Conjugation | Biotin |
| Host | Rabbit |
| Source | KLH conjugated synthetic peptide derived from human DHFR |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1ug/ul |
| Purification | Purified by Protein A. |
| Storage Buffer | Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Store at -20C for 12 months. |
| Target | |
| Gene ID | 1719 |
| Swiss Prot | P00374 |
| Subcellular location | Cytoplasm |
| Synonyms | DHFR; DHFRP1; Dihydrofolate reductase; DYR; DYR_HUMAN; EC 1.5.1.3. |
| Background | DHFR catalyzes the NADPH-dependent reduction of dihydrofolate to tetrahydrofolate, and is a crucial enzyme for the synthesis of purines, pyrimidines and some amino acids. Inhibition of the activity of this enzyme leads to arrest of DNA synthesis and cell death. Gene expression of methotrexate (MTX)-resistant variants of DHFR in normal hematopoietic cells is a potential strategy to permit administration of larger doses of MTX by alleviating drug toxicity in normal cells and tissues that are drug sensitive. |
| Application Dilution | |
| IHC-P | |
| IHC-F | |
Frequently asked questions
Which applications is DHFR Polyclonal Antibody, Biotin Conjugated (bs-9058R-Biotin) validated for, and at what dilution?
bs-9058R-Biotin is validated for IHC-P, IHC-F.
Which species does DHFR Polyclonal Antibody, Biotin Conjugated (bs-9058R-Biotin) react with?
Tested reactivity: Human, Mouse.
How should bs-9058R-Biotin be stored?
Store at -20C for 12 months. Storage buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
What immunogen was used to raise DHFR Polyclonal Antibody, Biotin Conjugated (bs-9058R-Biotin)?
KLH conjugated synthetic peptide derived from human DHFR