Overview |
bs-9434R |
APC70 Polyclonal Antibody |
WB, IHC-P, IF(IHC-P) |
Human |
Mouse, Rat, Dog, Cow, Pig, Horse, Rabbit |
Specifications |
Unconjugated |
Rabbit |
KLH conjugated synthetic peptide derived from human CRSP complex subunit 7/ARC70 |
Polyclonal |
#REF! |
IgG |
1ug/ul |
Purified by Protein A. |
0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
Shipped at 4_. Store at -20_ for one year. Avoid repeated freeze/thaw cycles. |
Target |
9441 |
O95402 |
Nucleus |
CRSP7; CRSP70; Mediator of RNA polymerase II transcription subunit 26; Activator-recruited cofactor 70 kDa component; ARC70; Cofactor required for Sp1 transcriptional activation subunit 7; CRSP complex subunit 7; Mediator complex subunit 26; Transcriptional coactivator CRSP70; MED26 |
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. |
Application Dilution |
WB |
1:300-5000 |
IHC-P |
1:200-400 |
IF(IHC-P) |
1:50-200 |