| Overview |
| bs-9477R-Biotin |
| CMYA2 Polyclonal Antibody, Biotin Conjugated |
| IHC-P |
| Human, Mouse, Rat |
| Specifications |
| Biotin |
| Rabbit |
| KLH conjugated synthetic peptide derived from human CMYA2/PDE4DIP |
| 1501-1600/2365 |
| Polyclonal |
| IgG |
| 1ug/ul |
| Purified by Protein A. |
| Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| Store at -20°C for 12 months. |
| Target |
| 9659 |
| Cardiomyopathy associated protein 2; Cardiomyopathy-associated protein 2; CMYA2; MMGL; MYOME_HUMAN; Myomegalin; Pde4dip; Phosphodiesterase 4D interacting protein; Phosphodiesterase 4D-interacting protein. |
| May function as an anchor sequestering components of the cAMP-dependent pathway to Golgi and/or centrosomes.Myomegalin, is a 2,346 amino acid protein that contains one NBPF domain and localizes to the nucleus, cytoplasm, centrosome and Golgi apparatus. Expressed at high levels in fetal and adult heart and at lower levels in brain and placenta, myomegalin is thought to function as an anchoring protein that sequesters members of the cAMP-dependent pathway to the Golgi and to centrosomes, thereby mediating cAMP pathway dynamics. Translocations in the gene that encodes myomegalin are associated with myeloproliferative disorders (MBDs), a group of diseases caused by an overproduction of blood cells. Myomegalin exists as twelve isoforms due to alternative splicing events. |
| Application Dilution |
| IHC-P |
1:200-400 |
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