REEP5 Polyclonal Antibody, Cy3 Conjugated

Applications

  • WB
  • IF(IHC-P)

Reactivity

  • Human
  • Mouse
  • Rat
Overview
Catalog # bs-9481R-Cy3
Product Name REEP5 Polyclonal Antibody, Cy3 Conjugated
Applications WB, IF(IHC-P)
Reactivity Human, Mouse, Rat
Specifications
Conjugation Cy3
Host Rabbit
Source KLH conjugated synthetic peptide derived from human REEP5
Immunogen Range 101-189/189
Clonality Polyclonal
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Condition Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Target
Gene ID 7905
Synonyms C5orf18; DP1; Polyposis locus protein 1; Receptor expression enhancing protein 5; Receptor expression-enhancing protein 5; TB2; TB2 protein; D5S346;REEP5_HUMAN.
Background REEP5 is a 189 amino acid multi-pass membrane protein. Thought to promote the functional cell surface expression of olfactory receptors, REEP5 belongs to the DP1 family and is encoded by a gene that maps to chromosome 5. With 181 million base pairs encoding around 1,000 genes, chromosome 5 is about 6% of human genomic DNA. Chromosome 5 is associated with Cockayne syndrome through the ERCC8 gene and familial adenomatous polyposis through the adenomatous polyposis coli (APC) tumor suppressor gene. Treacher Collins syndrome is also chromosome 5 associated and is caused by insertions or deletions within the TCOF1 gene. Deletion of the p arm of chromosome 5 leads to Cri du chat syndrome. Deletion of 5q or chromosome 5 altogether is common in therapy-related acute myelogenous leukemias and myelodysplastic syndrome.
Application Dilution
WB 1:300-5000
IF(IHC-P) 1:50-200