JMJD7 Polyclonal Antibody, AbBy Fluor-594 Conjugated
Applications
Reactivity
| Overview | |
| Catalog # | bs-9486R-BF594 |
| Product Name | JMJD7 Polyclonal Antibody, AbBy Fluor-594 Conjugated |
| Applications |
WB
IF(IHC-P)
|
| Reactivity | Human, Mouse, Rat |
| Specifications | |
| Conjugation | AbBy Fluor-594 |
| Host | Rabbit |
| Source | KLH conjugated synthetic peptide derived from human JMJD7 |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1ug/ul |
| Purification | Purified by Protein A. |
| Storage Buffer | Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Store at -20C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target | |
| Synonyms | JmjC domain-containing protein 7; JMJD7; JMJD7_HUMAN; Jumonji domain containing 7; Jumonji domain-containing protein 7. |
| Background | A crucial regulator of chromatin dynamics and DNA transcription is the covalent modification and methylation of histones. Generally, methylation of certain lysine residues on Histone H3 and Histone H4 can be associated with transcriptionally active or inactive chromatin. This regulation has profound effects on the expression of genes and is part of an epigenetic memory network that determines cell fate. JMJD7 (Jumonji domain-containing protein 7) is a member of a family of JMJC domain-containing histone demethylases that are directly involved in removing methyl residues from distinct and unique lysine residues. These actions are implicated in gene expression and the regulation of cell senescence. JMJC domain-containing histone demethylases are also likely involved in development via their ability to regulate gene expression. JMJD7 contains one JMJC domain and was originally thought to be an alternatively spliced isoform of PLA2G4B. |
| Application Dilution | |
| WB | 1:300-5000 |
| IF(IHC-P) | 1:50-200 |
Frequently asked questions
Which applications is JMJD7 Polyclonal Antibody, AbBy Fluor-594 Conjugated (bs-9486R-BF594) validated for, and at what dilution?
bs-9486R-BF594 is validated for WB (1:300-5000); IF(IHC-P) (1:50-200). These are recommended starting dilutions; optimal dilutions should be determined by the end user.
Which species does JMJD7 Polyclonal Antibody, AbBy Fluor-594 Conjugated (bs-9486R-BF594) react with?
Tested reactivity: Human, Mouse, Rat.
How should bs-9486R-BF594 be stored?
Store at -20C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. Storage buffer: Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
What immunogen was used to raise JMJD7 Polyclonal Antibody, AbBy Fluor-594 Conjugated (bs-9486R-BF594)?
KLH conjugated synthetic peptide derived from human JMJD7
What are the excitation and emission wavelengths of the AbBy Fluor-594 conjugate (bs-9486R-BF594)?
AbBy Fluor-594 on bs-9486R-BF594: excitation / emission 590nm/617nm.