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Factor XI light chain Polyclonal Antibody, PE-Cy5.5 Conjugated

Applications

  • WB

Predicted Reactivity

  • Human
  • Mouse
  • Rat
  • Dog
  • Sheep
  • Rabbit
Overview
Catalog # bs-9502R-PE-Cy5.5
Product Name Factor XI light chain Polyclonal Antibody, PE-Cy5.5 Conjugated
Applications
WB
Predicted Reactivity Human, Mouse, Rat, Dog, Sheep, Rabbit
Specifications
Conjugation PE-Cy5.5
Host Rabbit
Source KLH conjugated synthetic peptide derived from human Coagulation factor XIa light chain
Clonality Polyclonal
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage Condition Store at -20C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Target
Gene ID 2160
Synonyms Coagulation factor XI; Coagulation factor XIa light chain; F11; FA11_HUMAN; FXI; MGC141891; Plasma thromboplastin antecedent; PTA; Factor XI.
Background This gene encodes coagulation factor XI of the blood coagulation cascade. This protein is present in plasma as a zymogen, which is a unique plasma coagulation enzyme because it exists as a homodimer consisting of two identical polypeptide chains linked by disulfide bonds. During activation of the plasma factor XI, an internal peptide bond is cleaved by factor XIIa (or XII) in each of the two chains, resulting in activated factor XIa, a serine protease composed of two heavy and two light chains held together by disulfide bonds. This activated plasma factor XI triggers the middle phase of the intrisic pathway of blood coagulation by activating factor IX. Defects in this factor lead to Rosenthal syndrome, a blood coagulation abnormality. [provided by RefSeq, Jul 2008].
Application Dilution
WB 1:300-5000

Frequently asked questions

Which applications is Factor XI light chain Polyclonal Antibody, PE-Cy5.5 Conjugated (BS-9502R-PE-CY5-5) validated for, and at what dilution?

BS-9502R-PE-CY5-5 is validated for WB (1:300-5000). These are recommended starting dilutions; optimal dilutions should be determined by the end user.

How should BS-9502R-PE-CY5-5 be stored?

Store at -20C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. Storage buffer: Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

What immunogen was used to raise Factor XI light chain Polyclonal Antibody, PE-Cy5.5 Conjugated (BS-9502R-PE-CY5-5)?

KLH conjugated synthetic peptide derived from human Coagulation factor XIa light chain

What are the excitation and emission wavelengths of the PE-Cy5.5 conjugate (BS-9502R-PE-CY5-5)?

PE-Cy5.5 on BS-9502R-PE-CY5-5: excitation / emission 488nm/694nm.