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PROCR Polyclonal Antibody

Applications

  • WB
  • IHC-P
  • IF(IHC-P)

Reactivity

  • Mouse

Predicted Reactivity

  • Human
  • Rat
Overview
Catalog # bs-9506R
Product Name PROCR Polyclonal Antibody
Applications WB, IHC-P, IF(IHC-P)
Reactivity Mouse
Predicted Reactivity Human, Rat
Specifications
Conjugation Unconjugated
Host Rabbit
Source KLH conjugated synthetic peptide derived from human EPCR/CD201
Clonality Polyclonal
Clone # #REF!
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage Condition Shipped at 4_. Store at -20_ for one year. Avoid repeated freeze/thaw cycles.
Target
Gene ID 10544
Subcellular location Extracellular
Synonyms Activated protein C receptor; APC receptor; APCR; CCCA; CCD41; CD201 antigen; centrocyclin; Endothelial cell protein C receptor; MGC23024; PROCR; EPCR_HUMAN; CD201.
Background EPCR is a receptor for activated protein C, a serine protease activated by and involved in the blood coagulation pathway. It is an N glycosylated type I membrane protein that enhances the activation of protein C. Mutations in this gene have been associated with venous thromboembolism and myocardial infarction, as well as with late fetal loss during pregnancy. It is expressed strongly in the endothelial cells of arteries and veins in heart and lung. It is overexpressed in several human non-Pgp multidrug resistant (MDR) tumor cell lines. Whether and how anti-coagulant and anti-inflammatory functions of EPCR facilitate oncogenesis and/or drug resistance is unclear.
Application Dilution
WB 1:300-5000
IHC-P 1:200-400
IF(IHC-P) 1:50-200