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PIGA Polyclonal Antibody, Biotin Conjugated

Applications

  • WB
  • IHC-P

Reactivity

  • Human
  • Mouse
  • Rat
Overview
Catalog # bs-9524R-Biotin
Product Name PIGA Polyclonal Antibody, Biotin Conjugated
Applications
WB IHC-P
Reactivity Human, Mouse, Rat
Specifications
Conjugation Biotin
Host Rabbit
Source KLH conjugated synthetic peptide derived from human PIGA
Clonality Polyclonal
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage Condition Store at -20C for 12 months.
Target
Gene ID 5277
Synonyms GlcNAc PI synthesis protein; GlcNAc-PI synthesis protein; GPI3; Phosphatidylinositol glycan anchor biosynthesis class A; phosphatidylinositol glycan anchor biosynthesis, class A paroxysmal nocturnal hemoglobinuria; Phosphatidylinositol N-acetylglucosaminyltransferase subunit A; PIG A; PIG-A; PIGA_HUMAN; Phosphatidylinositol-glycan biosynthesis class A protein; PIG-A.
Background PIGA belongs to the glycosyltransferase 1 family and is necessary for the synthesis of N-acetylglucosaminyl-phosphatidylinositol, the very early intermediate in GPI-anchor biosynthesis. Defects in PIGA are the cause of paroxysmal nocturnal hemoglobinuria (PNH) which is an acquired hemolytic blood disorder characterized by chronic hemolysis with hemoglobinuria, increased tendency to venous thrombosis, and variable degrees of bone marrow failure.
Application Dilution
WB 1:300-5000
IHC-P 1:200-400

Frequently asked questions

Which applications is PIGA Polyclonal Antibody, Biotin Conjugated (bs-9524R-Biotin) validated for, and at what dilution?

bs-9524R-Biotin is validated for WB (1:300-5000); IHC-P (1:200-400). These are recommended starting dilutions; optimal dilutions should be determined by the end user.

Which species does PIGA Polyclonal Antibody, Biotin Conjugated (bs-9524R-Biotin) react with?

Tested reactivity: Human, Mouse, Rat.

How should bs-9524R-Biotin be stored?

Store at -20C for 12 months. Storage buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

What immunogen was used to raise PIGA Polyclonal Antibody, Biotin Conjugated (bs-9524R-Biotin)?

KLH conjugated synthetic peptide derived from human PIGA