Geminin Polyclonal Antibody
Applications
Reactivity
| Overview | |
| Catalog # | bs-9536R |
| Product Name | Geminin Polyclonal Antibody |
| Applications |
IHC-P
IHC-F
IF
FLOW-CYT
|
| Reactivity | Human, Mouse, Rat |
| Specifications | |
| Conjugation | Unconjugated |
| Host | Rabbit |
| Source | KLH conjugated synthetic peptide derived from human Geminin |
| Immunogen Range | 111-209/209 |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1ug/ul |
| Purification | Purified by Protein A. |
| Storage Buffer | 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles. |
| Target | |
| Gene ID | 51053 |
| Swiss Prot | O75496 |
| Subcellular location | Cytoplasm |
| Synonyms | Gem; Geminin; GMNN |
| Background | Inhibits DNA replication by preventing the incorporation of MCM complex into pre-replication complex (pre-RC). It is degraded during the mitotic phase of the cell cycle. Its destruction at the metaphase-anaphase transition permits replication in the succeeding cell cycle. Inhibits the transcriptional activity of a subset of Hox proteins, enrolling them in cell proliferative control. |
| Application Dilution | |
| IHC-P | WB1:300-5000 |
| IHC-F | IHC-P1:200-400 |
| IF | IHC-P1:50-200 |
| Flow-Cyt | |