SLC39A11 Polyclonal Antibody, FITC Conjugated
Applications
Reactivity
| Overview | |
| Catalog # | bs-9635R-FITC |
| Product Name | SLC39A11 Polyclonal Antibody, FITC Conjugated |
| Applications |
WB
IF
|
| Reactivity | Human, Mouse, Rat |
| Specifications | |
| Conjugation | FITC |
| Host | Rabbit |
| Source | KLH conjugated synthetic peptide derived from human SLC39A11 |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1ug/ul |
| Purification | Purified by Protein A. |
| Storage Buffer | Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Store at -20C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target | |
| Gene ID | 201266 |
| Synonyms | C17orf26; S39AB_HUMAN; SLC39A11; Solute carrier family 39 metal ion transporter member 11; Solute carrier family 39 member 11; Zinc transporter ZIP11; ZIP-11; ZIP11; Zrt and Irt like protein 11; Zrt- and Irt-like protein 11. |
| Background | Zinc is an essential cofactor that is involved in cell growth and development, as well as in protein, nucleic acid and lipid metabolism. The transport of zinc across the cell membrane is crucial for correct enzyme and overall cell function. SLC39A11 (solute carrier family 39 (metal ion transporter), member 11), also known as ZIP11 (Zrt- and Irt-like protein 11), is a 342 amino acid multi-pass membrane protein belonging to the ZIP transporter family. Expressed as multiple alternatively spliced isoforms, SLC39A11 acts as a zinc-influx transporter and is encoded by a gene located on human chromosome 17, which comprises over 2.5% of the human genome and encodes over 1,200 genes, some of which are involved in tumor suppression and in the pathogenesis of Li-Fraumeni syndrome, early onset breast cancer and a predisposition to cancers of the ovary, colon, prostate gland and fallopian tubes. |
| Application Dilution | |
| WB | 1:300-5000 |
| IF | IHC-P1:50-200 |
Frequently asked questions
Which applications is SLC39A11 Polyclonal Antibody, FITC Conjugated (bs-9635R-FITC) validated for, and at what dilution?
bs-9635R-FITC is validated for WB (1:300-5000); IF(IHC-P) (1:50-200). These are recommended starting dilutions; optimal dilutions should be determined by the end user.
Which species does SLC39A11 Polyclonal Antibody, FITC Conjugated (bs-9635R-FITC) react with?
Tested reactivity: Human, Mouse, Rat.
How should bs-9635R-FITC be stored?
Store at -20C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. Storage buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
What immunogen was used to raise SLC39A11 Polyclonal Antibody, FITC Conjugated (bs-9635R-FITC)?
KLH conjugated synthetic peptide derived from human SLC39A11
What are the excitation and emission wavelengths of the FITC conjugate (bs-9635R-FITC)?
FITC on bs-9635R-FITC: excitation / emission 494nm/518nm.