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DENND2C Polyclonal Antibody, HRP Conjugated

Applications

  • WB
  • IHC-P

Reactivity

  • Human

Predicted Reactivity

  • Mouse
  • Cow
  • Sheep
  • Horse
  • Rabbit
Overview
Catalog # bs-9667R-HRP
Product Name DENND2C Polyclonal Antibody, HRP Conjugated
Applications
WB IHC-P
Reactivity Human
Predicted Reactivity Mouse, Cow, Sheep, Horse, Rabbit
Specifications
Conjugation HRP
Host Rabbit
Source KLH conjugated synthetic peptide derived from human DENND2C
Clonality Polyclonal
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage Condition Store at -20C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Target
Gene ID 163259
Synonyms DENN/MADD domain containing 2C; dJ1156J9.1; DKFZp686G0351; DKFZp686N1631; DKFZp779P1149; FLJ37099; RP5-1156J9.1; DEN2C_HUMAN.
Background DENND2C is a 928 amino acid protein that contains a dDENN domain, a DENN domain, and a uDENN domain and exists as three isoforms as a result of alternative splicing. The DENND2C protein is thought to target to actin filaments and control Rab9-dependent trafficking of mannose-6-phosphate receptor to lysosomes. The gene encoding DENND2C maps to human chromosome 1, the largest human chromosome which spans about 260 million base pairs and makes up 8% of the human genome. Other notable genes located on chromosome 1 include LMNA, which is associated with the rare aging disease Hutchinson-Gilford progeria, and the MUTYH gene, which is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome.
Application Dilution
WB 1:300-5000
IHC-P 1:200-400

Frequently asked questions

Which applications is DENND2C Polyclonal Antibody, HRP Conjugated (bs-9667R-HRP) validated for, and at what dilution?

bs-9667R-HRP is validated for WB (1:300-5000); IHC-P (1:200-400). These are recommended starting dilutions; optimal dilutions should be determined by the end user.

Which species does DENND2C Polyclonal Antibody, HRP Conjugated (bs-9667R-HRP) react with?

Tested reactivity: Human. Predicted reactivity (expected from sequence homology but not yet tested): Mouse, Cow, Sheep, Horse, Rabbit.

How should bs-9667R-HRP be stored?

Store at -20C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. Storage buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

What immunogen was used to raise DENND2C Polyclonal Antibody, HRP Conjugated (bs-9667R-HRP)?

KLH conjugated synthetic peptide derived from human DENND2C