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ANGEL2 Polyclonal Antibody, Cy5.5 Conjugated

Applications

  • WB
  • IF(IHC-P)

Reactivity

  • Human
  • Mouse
  • Rat
Overview
Catalog # bs-9742R-Cy5.5-100uL
Product Name ANGEL2 Polyclonal Antibody, Cy5.5 Conjugated
Applications
WB IF(IHC-P)
Reactivity Human, Mouse, Rat
Specifications
Conjugation Cy5.5
Host Rabbit
Source KLH conjugated synthetic peptide derived from human ANGEL2
Clonality Polyclonal
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage Condition Store at -20C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Target
Gene ID 90806
Synonyms NGE2_HUMAN; Angel homolog 2; angel2; Protein angel homolog 2.
Background ANGEL2 is a 544 amino acid protein that belongs to the CCR4/nocturin family and exists as two alternatively spliced isoforms. The CCR4 family of proteins are 3_5_-deadenylases that function in the first step of the degradation of poly(A) mRNA. The CCR4 family most likely displays both RNA and ssDNA substrate preferences, thereby implicating a potential role in many regulatory processes. The ANGEL2 gene maps to human chromosome 1 (1q32.3), which is the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome. Chromosome 1 contains about 3,000 genes, and considering the great number of genes there are also a large number of diseases associated with it. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons disease, Gaucher disease and Usher syndrome are also associated with chromosome 1.
Application Dilution
WB 1:300-5000
IF(IHC-P) 1:50-200

Frequently asked questions

Which applications is ANGEL2 Polyclonal Antibody, Cy5.5 Conjugated (BS-9742R-CY5-5) validated for, and at what dilution?

BS-9742R-CY5-5 is validated for WB (1:300-5000); IF(IHC-P) (1:50-200). These are recommended starting dilutions; optimal dilutions should be determined by the end user.

Which species does ANGEL2 Polyclonal Antibody, Cy5.5 Conjugated (BS-9742R-CY5-5) react with?

Tested reactivity: Human, Mouse, Rat.

How should BS-9742R-CY5-5 be stored?

Store at -20C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. Storage buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

What immunogen was used to raise ANGEL2 Polyclonal Antibody, Cy5.5 Conjugated (BS-9742R-CY5-5)?

KLH conjugated synthetic peptide derived from human ANGEL2

What are the excitation and emission wavelengths of the Cy5.5 conjugate (BS-9742R-CY5-5)?

Cy5.5 on BS-9742R-CY5-5: excitation / emission 675nm/694nm.

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