ANKMY1 Polyclonal Antibody, PE Conjugated
Applications
Reactivity
| Overview | |
| Catalog # | bs-9744R-PE-100uL |
| Product Name | ANKMY1 Polyclonal Antibody, PE Conjugated |
| Applications |
WB
IF(IHC-P)
|
| Reactivity | Human |
| Specifications | |
| Conjugation | PE |
| Host | Rabbit |
| Source | KLH conjugated synthetic peptide derived from human ANKMY1 |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1ug/ul |
| Purification | Purified by Protein A. |
| Storage Buffer | Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Store at -20C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target | |
| Gene ID | 51281 |
| Synonyms | ankyrin repeat and MYND domain containing 1; Testis specic ankyrin like protein 1; TSAL1; Zinc finger MYND domain containing protein 13; ZMYND13; ANKY1_HUMAN. |
| Background | Ankyrins are membrane adaptor molecules that play important roles in coupling integral membrane proteins to the spectrin-based cytoskeleton network. Mutations of ankyrin genes lead to severe genetic diseases such as fatal cardiac arrhythmias and hereditary spherocytosis. ANKMY1 (ankyrin repeat and MYND domain containing 1), also known as ZMYND13 or TSAL1, is a 941 amino acid protein that contains seven ANK repeats, three MORN repeats and one MYND-type zinc finger. MORN repeats were first identified in junctophilins, cytoplasmic proteins involved in junctions between the plasma membrane and the ER/SR membrane. The presence of MORN repeats suggests that ANKMY1 may interact with the plasma membrane. The MYND domain consists of a cluster of cysteine and histidine residues, arranged with an invariant spacing to form a potential zinc-binding motif which may be involved in protein-protein interactions. Three isoforms of ANKMY1 exists due to alternative splicing events. |
| Application Dilution | |
| WB | 1:300-5000 |
| IF(IHC-P) | |
Frequently asked questions
Which applications is ANKMY1 Polyclonal Antibody, PE Conjugated (bs-9744R-PE) validated for, and at what dilution?
bs-9744R-PE is validated for WB (1:300-5000). These are recommended starting dilutions; optimal dilutions should be determined by the end user.
Which species does ANKMY1 Polyclonal Antibody, PE Conjugated (bs-9744R-PE) react with?
Tested reactivity: Human.
How should bs-9744R-PE be stored?
Store at -20C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. Storage buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
What immunogen was used to raise ANKMY1 Polyclonal Antibody, PE Conjugated (bs-9744R-PE)?
KLH conjugated synthetic peptide derived from human ANKMY1
What are the excitation and emission wavelengths of the PE conjugate (bs-9744R-PE)?
PE on bs-9744R-PE: excitation / emission 496,564nm/578nm.