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ANKRD20A3 Polyclonal Antibody

Applications

  • ELISA
  • IHC-P
  • IHC-F
  • IF

Reactivity

  • Human
Overview
Catalog # bs-9747R-100uL
Product Name ANKRD20A3 Polyclonal Antibody
Applications
ELISA IHC-P IHC-F IF
Reactivity Human
Specifications
Conjugation Unconjugated
Host Rabbit
Source KLH conjugated synthetic peptide derived from human ANKRD20A3
Immunogen Range 521-620/823
Clonality Polyclonal
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage Condition Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.
Target
Gene ID 441425
Synonyms Ankyrin repeat domain 20 family member A3; Ankyrin repeat domain 20A related; Ankyrin repeat domain containing protein 20A3; MGC176486; MGC198508; A20A3_HUMAN.
Background Ankyrins are membrane adaptor molecules that play important roles in coupling integral membrane proteins to the spectrin-based cytoskeleton network. Mutations of ankyrin genes lead to severe genetic diseases such as fatal cardiac arrhythmias and hereditary spherocytosis. ANKRD20A (ankyrin repeat domain-containing protein 20A) is an 823 amino acid protein that contains five ANK repeats. The gene encoding ANKRD20A maps to chromosome 9, which consists of about 145 million bases and encodes nearly 900 genes. Considered to play a role in gender determination, deletion of the distal portion of 9p can lead to development of male to female sex reversal, the phenotype of a female with a male X,Y genotype. Hereditary hemorrhagic telangiectasia, which is characterized by harmful vascular defects, and familial dysautonomia are associated with chromosome 9. Also, chromosome 9 is partnered with chromosome 22 in the translocation leading to the aberrant production of BCR-ABL fusion protein often found in leukemias.
Application Dilution
ELISA IHC-P1:200-400
IHC-P IFIHC-P1:50-200
IHC-F
IF

Frequently asked questions

Which applications is ANKRD20A3 Polyclonal Antibody (bs-9747R) validated for, and at what dilution?

bs-9747R is validated for IHC-P (1:200-400); IF(IHC-P) (1:50-200). These are recommended starting dilutions; optimal dilutions should be determined by the end user.

Which species does ANKRD20A3 Polyclonal Antibody (bs-9747R) react with?

Tested reactivity: Human.

How should bs-9747R be stored?

Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles. Storage buffer: 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

What immunogen was used to raise ANKRD20A3 Polyclonal Antibody (bs-9747R)?

KLH conjugated synthetic peptide derived from human ANKRD20A3 Immunogen range: 521-620/823.

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