Plasminogen activator A Polyclonal Antibody

Applications

  • IHC-P
  • IF(IHC-P)

Reactivity

  • Bacteria
Overview
Catalog # bs-9846R
Product Name Plasminogen activator A Polyclonal Antibody
Applications IHC-P, IF(IHC-P)
Reactivity Bacteria
Specifications
Conjugation Unconjugated
Host Rabbit
Source KLH conjugated synthetic peptide derived from Streptococcus uberis PauA protein
Immunogen Range 250-286/286
Clonality Polyclonal
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for 12 months.
Target
Gene ID 24161944
Swiss Prot B9DW72
Subcellular location Extracellular, Secreted
Synonyms PauA; Plasminogen activator A; SUB1785; Streptokinase; Streptococcus uberis
Background Plasminogen activator A (PauA) is a Streptococcus uberis protein that functions similarly to proteins within the Staphylokinase/Streptokinase family. Streptococcus uberis is a common cause of infection and inflammatory disease in the bovine udder. Inflammation of breast tissue (mastitis) has been recognized as a serious threat to the welfare of the dairy cow and has a severe economic impact on the dairy industry. S. uberis has been shown to specifically activate bovine and ovine plasminogen and this is mediated by the extracellular protein, plasminogen activator uberis (PauA), which has a molecular mass of around 30 kDa. It has been postulated that activation of plasminogen by PauA may facilitate early bacterial colonization of the lactating gland by promoting the release of nutrients which are likely to be restricted in milk. (https://www.ncbi.nlm.nih.gov/pubmed/10483719).
Application Dilution
IHC-P 1:200-400
IF(IHC-P) 1:50-200