TFCP2C Polyclonal Antibody


  • WB
  • IHC-P
  • IF(IHC-P)


  • Human
  • Mouse
  • Rat
Catalog # bs-9852R
Product Name TFCP2C Polyclonal Antibody
Applications WB, IHC-P, IF(IHC-P)
Reactivity Human, Mouse, Rat
Conjugation Unconjugated
Host Rabbit
Source KLH conjugated synthetic peptide derived from human TFCP2C
Clonality Polyclonal
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for 12 months.
Gene ID 7024
Synonyms Alpha globin transcription factor CP2; CP2; LBP 1C; LBP1C; LSF; SAA3 enhancer factor; SEF; TFCP2; TFCP2C; Transcription factor CP2; Transcription factor LSF; TFCP2_HUMAN.
Background CP2 family gene products are reported to be involved in a-globin gene expression. Mouse CP2c (also known as a-CP2/CP2/LSF/UBP-1) is a homologue of human LBP-1c with 96% amino acid sequence identity. CP2c was initially identified as an activator of the mouse a-globin gene, which binds to the consensus DNA-binding sequence CNRG-N6-CNR(G/C) within a promoter element overlapping the CCAAT box. The transcriptional activity of CP2c was increased during induced differentiation of MEL cells and associated globin gene transcription. CP2c is also likely to be involved in regulation of non-globin erythroid-specific genes. It was reported that congenital erythropoietic porphyria was caused by the mutations in GATA-1 and CP2c binding sites within the promoter of the uroporphyrinogen III synthase gene, the fourth enzyme in the heme biosynthetic pathway.
Application Dilution
WB 1:300-1000
IHC-P 1:200-400
IF(IHC-P) 1:50-200