Hemoglobin alpha Polyclonal Antibody

Applications

  • IHC-P
  • IF(IHC-P)

Reactivity

  • Human
Overview
Catalog # bs-9889R
Product Name Hemoglobin alpha Polyclonal Antibody
Applications IHC-P, IF(IHC-P)
Reactivity Human
Specifications
Conjugation Unconjugated
Host Rabbit
Source KLH conjugated synthetic peptide derived from human Hemoglobin alpha
Immunogen Range 10-60/142
Clonality Polyclonal
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for 12 months.
Target
Gene ID 3039
Swiss Prot P69905
Synonyms HBH; HBA-T3; Hemoglobin subunit alpha; Alpha-globin; Hemoglobin alpha chain; HBA1
Background The human alpha globin gene cluster located on chromosome 16 spans about 30 kb and includes seven loci: 5'- zeta - pseudozeta - mu - pseudoalpha-1 - alpha-2 - alpha-1 - theta - 3'. The alpha-2 (HBA2) and alpha-1 (HBA1) coding sequences are identical. These genes differ slightly over the 5' untranslated regions and the introns, but they differ significantly over the 3' untranslated regions. Two alpha chains plus two beta chains constitute HbA, which in normal adult life comprises about 97% of the total hemoglobin; alpha chains combine with delta chains to constitute HbA-2, which with HbF (fetal hemoglobin) makes up the remaining 3% of adult hemoglobin. Alpha thalassemias result from deletions of each of the alpha genes as well as deletions of both HBA2 and HBA1; some nondeletion alpha thalassemias have also been reported. [provided by RefSeq, Jul 2008].
Application Dilution
IHC-P 1:200-400
IF(IHC-P) 1:50-200