SISP1 Polyclonal Antibody, PE-Cy5 Conjugated
Applications
Reactivity
| Overview | |
| Catalog # | bs-9898R-PE-Cy5-100uL |
| Product Name | SISP1 Polyclonal Antibody, PE-Cy5 Conjugated |
| Applications |
WB
|
| Reactivity | Human |
| Specifications | |
| Conjugation | PE-Cy5 |
| Host | Rabbit |
| Source | KLH conjugated synthetic peptide derived from human SISP1/GI24 |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1ug/ul |
| Purification | Purified by Protein A. |
| Storage Buffer | Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Store at -20C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target | |
| Subcellular location | Extracellular |
| Synonyms | C10orf54; GI24_HUMAN; Platelet receptor Gi24; PP2135; SISP1; stress induced secreted protein 1; UNQ730/PRO1412. |
| Background | Platelet receptor GI24, also known as SISP1 or PP2135, is a 311 amino acid single-pass type I membrane protein that contains one Ig-like (immunoglobulin-like) domain. GI24 is thought to contribute to tumor-invasive growth in the collagen matrix and is encoded by a gene that maps to human chromosome 10q22.1. Chromosome 10 contains over 800 genes, 135 million nucleotides and comprises nearly 4.5% of the human genome. PTEN is an important tumor suppressor gene located on chromosome 10 and, when defective, causes a genetic predisposition to cancer development known as Cowden syndrome. The chromosome 10 encoded gene ERCC6 is important for DNA repair and is linked to Cockayne syndrome which is characterized by extreme photosensitivity and premature aging. Tetrahydrobiopterin deficiency and a number of syndromes involving defective skull and facial bone fusion are also linked to chromosome 10. As with most trisomies, trisomy 10 is rare and is deleterious. |
| Application Dilution | |
| WB | 1:300-5000 |
Frequently asked questions
Which applications is SISP1 Polyclonal Antibody, PE-Cy5 Conjugated (bs-9898R-PE-Cy5) validated for, and at what dilution?
bs-9898R-PE-Cy5 is validated for WB (1:300-5000). These are recommended starting dilutions; optimal dilutions should be determined by the end user.
Which species does SISP1 Polyclonal Antibody, PE-Cy5 Conjugated (bs-9898R-PE-Cy5) react with?
Tested reactivity: Human.
How should bs-9898R-PE-Cy5 be stored?
Store at -20C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. Storage buffer: Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
What immunogen was used to raise SISP1 Polyclonal Antibody, PE-Cy5 Conjugated (bs-9898R-PE-Cy5)?
KLH conjugated synthetic peptide derived from human SISP1/GI24
What are the excitation and emission wavelengths of the PE-Cy5 conjugate (bs-9898R-PE-Cy5)?
PE-Cy5 on bs-9898R-PE-Cy5: excitation / emission 488nm/670nm.