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PGCP Polyclonal Antibody, AbBy Fluor-350 Conjugated

Applications

  • WB
  • IF(IHC-P)

Reactivity

  • Human
  • Mouse
  • Rat
Overview
Catalog # bs-9917R-BF350-100uL
Product Name PGCP Polyclonal Antibody, AbBy Fluor-350 Conjugated
Applications
WB IF(IHC-P)
Reactivity Human, Mouse, Rat
Specifications
Conjugation AbBy Fluor-350
Host Rabbit
Source KLH conjugated synthetic peptide derived from human PGCP
Clonality Polyclonal
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage Condition Store at -20C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Target
Gene ID 10404
Synonyms Plasma glutamate carboxypeptidase; CBPQ_HUMAN.
Background PGCP is a 472 amino acid secreted protein that is primarily detected in blood plasma. PGCP is a carboxypeptidase that potentially is involved in the hydrolysis of circulating peptides. Due to its upregulation in hepatocellular carcinoma (HCC), it is suspected that PGCP may be a potential serological marker for HCC. PGCP is a member of the Peptidase M28 family of proteins, which also includes PSM (prostate-specific membrane antigen), metallopeptidases and aminopeptidases. The gene encoding PGCP maps to chromosome 8, which is made up of nearly 146 million bases and encodes about 800 genes. Translocation of portions of chromosome 8 with amplifications of the c-Myc gene are found in some leukemias and lymphomas, and are typically associated with a poor prognosis.In humans, PGCP is found principally in blood plasma. It is a Carboxypeptidase that may play an important role in the hydrolysis of circulating peptides.
Application Dilution
WB 1:300-5000
IF(IHC-P) 1:50-200

Frequently asked questions

Which applications is PGCP Polyclonal Antibody, AbBy Fluor-350 Conjugated (bs-9917R-BF350) validated for, and at what dilution?

bs-9917R-BF350 is validated for WB (1:300-5000); IF(IHC-P) (1:50-200). These are recommended starting dilutions; optimal dilutions should be determined by the end user.

Which species does PGCP Polyclonal Antibody, AbBy Fluor-350 Conjugated (bs-9917R-BF350) react with?

Tested reactivity: Human, Mouse, Rat.

How should bs-9917R-BF350 be stored?

Store at -20C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. Storage buffer: Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

What immunogen was used to raise PGCP Polyclonal Antibody, AbBy Fluor-350 Conjugated (bs-9917R-BF350)?

KLH conjugated synthetic peptide derived from human PGCP

What are the excitation and emission wavelengths of the AbBy Fluor-350 conjugate (bs-9917R-BF350)?

AbBy Fluor-350 on bs-9917R-BF350: excitation / emission 346nm/442nm.

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