beta Amyloid (1-42) Monoclonal Antibody
Applications
Reactivity
Predicted Reactivity
| Overview | |
| Catalog # | bsm-0107m-100uL |
| Product Name | beta Amyloid (1-42) Monoclonal Antibody |
| Applications |
WB
IF(IHC-P)
IHC-P
|
| Reactivity | Rat |
| Predicted Reactivity | Human, Mouse |
| Specifications | |
| Conjugation | Unconjugated |
| Host | Mouse |
| Source | KLH conjugated synthetic peptide derived from human beta-Amyloid (1-42) |
| Clonality | Monoclonal |
| Clone # | 1F4 |
| Isotype | IgG |
| Concentration | Lot Dependent |
| Purification | Purified by Protein G. |
| Storage Buffer | 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles. |
| Target | |
| Gene ID | 351 |
| Background | The cerebral and vascular plaques associated with Alzheimer's disease are mainly composed of Amyloid beta peptides. beta Amyloid is derived from cleavage of the Amyloid precursor protein and varies in length from 39 to 43 amino acids. beta Amyloid [1-40], beta Amyloid [1-42], and beta Amyloid [1-43] peptides result from cleavage of Amyloid precursor protein after residues 40, 42, and 43, respectively. The cleavage takes place by gamma-secretase during the last Amyloid precursor protein processing step. beta Amyloid [1-40], beta Amyloid [1-42], and beta Amyloid [1-43] peptides are major constituents of the plaques and tangles that occur in Alzheimer's disease. beta Amyloid and peptides have been developed as tools for elucidating the biology of Alzheimer's disease. |
| Application Dilution | |
| WB | 1:200-400 |
| IF(IHC-P) | 1:50-200 |
| IHC-P | 1:50-200 |
Frequently asked questions
Which applications is beta Amyloid (1-42) Monoclonal Antibody (bsm-0107M) validated for, and at what dilution?
bsm-0107M is validated for WB (1:200-400); IF(IHC-P) (1:50-200); IHC-P (1:50-200). These are recommended starting dilutions; optimal dilutions should be determined by the end user.
Which species does beta Amyloid (1-42) Monoclonal Antibody (bsm-0107M) react with?
Tested reactivity: Rat. Predicted reactivity (expected from sequence homology but not yet tested): Human, Mouse.
How should bsm-0107M be stored?
Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles. Storage buffer: 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
What immunogen was used to raise beta Amyloid (1-42) Monoclonal Antibody (bsm-0107M)?
KLH conjugated synthetic peptide derived from human beta-Amyloid (1-42)