CRP(C11F2) Monoclonal Antibody, AbBy Fluor-488 Conjugated
Applications
Reactivity
| Overview | |
| Catalog # | bsm-0391M-BF488 |
| Product Name | CRP(C11F2) Monoclonal Antibody, AbBy Fluor-488 Conjugated |
| Applications |
WB
IF
|
| Reactivity | Human, Mouse, Rat |
| Specifications | |
| Conjugation | AbBy Fluor-488 |
| Host | Mouse |
| Source | Recombinded CRP protein |
| Clonality | Monoclonal |
| Clone # | C11F2 |
| Isotype | IgG |
| Concentration | 1ug/ul |
| Purification | Purified by Protein A. |
| Storage Buffer | Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Store at -20C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target | |
| Gene ID | 1401 |
| Swiss Prot | P02741 |
| Subcellular location | Secreted |
| Synonyms | C-reactive protein; C Reactive Protein; C reactive protein pentraxin related; CRP; MGC88244; PTX 1; PTX1; C-reactive protein(1-205); CRP_HUMAN; Pentraxin 1. |
| Background | C Reactive Protein is a major acute phase reactant synthesized primarily in the liver hepatocytes. It is a pentraxin (cyclic pentameric protein) compound of five identical nonglycosylated subunits of 206 amino acids each (m.w. 24 kDa), that are bound noncovalently to form the physiologic CRP molecule (m.w. 117.5 kDa). C Reactive Protein mediates activities associated with preimmune nonspecific host resistance. It is opsonic, an initiator of the classical complement cascade and an activator of monocytes/macrophages. CRP also binds to several nuclear components including chromatin, histones and snRNP, suggesting that it may play a role as a scavenger during cell necrosis. Studies have revealed that among other markers of inflammation, CRP shows the strongest association with cardiovascular events. Many clinical studies demonstrated that coronary mortality among patients with unstable angina and elevated CRP is significantly higher comparing with the patients without elevated CRP. Measurements of C reactive protein (hsCRP) in the patients with ischemic heart disease provide a novel method for detecting individuals at high risk of plaque rupture. |
| Application Dilution | |
| WB | 1:300-5000 |
| IF | ICC1:50-200 |
Frequently asked questions
Which applications is CRP(C11F2) Monoclonal Antibody, AbBy Fluor-488 Conjugated (bsm-0391M-BF488) validated for, and at what dilution?
bsm-0391M-BF488 is validated for WB (1:300-5000); IF(ICC) (1:50-200). These are recommended starting dilutions; optimal dilutions should be determined by the end user.
Which species does CRP(C11F2) Monoclonal Antibody, AbBy Fluor-488 Conjugated (bsm-0391M-BF488) react with?
Tested reactivity: Human, Mouse, Rat.
How should bsm-0391M-BF488 be stored?
Store at -20C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. Storage buffer: Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
What immunogen was used to raise CRP(C11F2) Monoclonal Antibody, AbBy Fluor-488 Conjugated (bsm-0391M-BF488)?
Recombinded CRP protein
What are the excitation and emission wavelengths of the AbBy Fluor-488 conjugate (bsm-0391M-BF488)?
AbBy Fluor-488 on bsm-0391M-BF488: excitation / emission 499nm/519nm.