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Endothelin-1(2C4) Monoclonal Antibody, Biotin Conjugated

Applications

  • WB
  • IHC-P

Reactivity

  • Human
  • Rat
Overview
Catalog # bsm-0954M-Biotin
Product Name Endothelin-1(2C4) Monoclonal Antibody, Biotin Conjugated
Applications WB, IHC-P
Reactivity Human, Rat
Specifications
Conjugation Biotin
Host Mouse
Source KLH conjugated synthetic peptide derived from human Endothelin-1
Immunogen Range 53-73/202
Clonality Monoclonal
Clone # 2C4
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein G.
Storage Buffer Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Condition Store at -20°C for 12 months.
Target
Gene ID 1906
Synonyms EDN 1; EDN1; EDN1 protein; Endothelin1; ET 1; ET1;
Background Endothelins (ET) show potent constrictor activity in vascular and non-vascular smooth muscle. This family of 21-amino acid peptides exists in at least three isoforms - ET-1, ET-2, and ET-3, and is produced in endothelial and epithelial cells. ET's can mediate biological effects in cells and tissues, and have been shown to bind to an ET receptor in the lung, kidney, heart, and liver. Endothelin 1 is expressed in lung, placental stem villi vessels and in cultured placental vascular smooth muscle cells.
Application Dilution
WB 1:300-5000
IHC-P 1:200-400