AFP (A2) Monoclonal Antibody

Applications

  • WB
  • ELISA
  • IHC-P
  • IF(IHC-P)

Reactivity

  • Human
  • Rat
Overview
Catalog # bsm-1621M
Product Name AFP (A2) Monoclonal Antibody
Applications WB, ELISA, IHC-P, IF(IHC-P)
Reactivity Human, Rat
Specifications
Conjugation Unconjugated
Host Mouse
Source Full length human AFP protein
Clonality Monoclonal
Clone # A2
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein G.
Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300
Storage Condition Store at -20°C for 12 months.
Target
Gene ID 174
Swiss Prot P02771
Synonyms AFPD; FETA; HPAFP; Alpha-fetoprotein; Alpha-1-fetoprotein; Alpha-fetoglobulin; AFP
Background Alpha-fetoprotein (AFP) is a major plasma protein produced by the yolk sac and the liver during fetal life. Alpha-fetoprotein expression in adults is often associated with hepatoma or teratoma. However, hereditary persistance of alpha-fetoprotein may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and the alpha-fetoprotein and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. Alpha-fetoprotein is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. The level of alpha-fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly.
Application Dilution
WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IF(IHC-P) 1:50-200