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Morphine(2F11) Monoclonal Antibody

Applications

  • WB
  • ELISA
  • IHC-F
  • IF
  • IHC-P

Reactivity

  • Others
Overview
Catalog # bsm-2129M-100uL
Product Name Morphine(2F11) Monoclonal Antibody
Applications
WB ELISA IHC-F IF IHC-P
Reactivity Others
Specifications
Conjugation Unconjugated
Host Mouse
Source KLH conjugated Morphine molecular modified
Clonality Monoclonal
Clone # 2F11
Isotype IgG
Concentration Lot Dependent
Purification Purified by Protein G.
Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage Condition Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.
Target
Synonyms Morphine 6.
Background Morphine is thought to produce reinforcement phenomena via stimulation of mu, delta, and kappa opioid receptors that regulate stress perception, pain control, reward behavior, and neurohormone secretion in reward-relevant brain systems. It has the highest affinity for mu, followed by delta and kappa. Rapid activation of the mu opioid receptor by morphine results in a euphoric phenotype, thus conferring the reinforcing effects of the drug. This activation is accompanied by extracellular dopamine release, which alters several events related to the cAMP signal transduction pathway. Of particular significance is that CREB seems to be modified by morphine, thereby affecting addictive behavioral phenomena, such as withdrawal symptoms.
Application Dilution
WB 1:300-5000
ELISA 1:200-400
IHC-F 1:50-200
IF 1:50-100
IHC-P 1:100-500

Frequently asked questions

Which applications is Morphine(2F11) Monoclonal Antibody (bsm-2129M) validated for, and at what dilution?

bsm-2129M is validated for WB (1:300-5000); ELISA (1:200-400); IHC-F (1:50-200); IF (1:50-100); IHC-P (1:100-500). These are recommended starting dilutions; optimal dilutions should be determined by the end user.

How should bsm-2129M be stored?

Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles. Storage buffer: 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

What immunogen was used to raise Morphine(2F11) Monoclonal Antibody (bsm-2129M)?

KLH conjugated Morphine molecular modified

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