human CD43/APC
Applications
Reactivity
| Overview | |
| Catalog # | bsm-30036m-apc-100t |
| Product Name | human CD43/APC |
| Applications |
FCM
|
| Reactivity | Human |
| Specifications | |
| Conjugation | Unconjugated |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone # | 4C7 |
| Isotype | IgG1/Kappa |
| Concentration | n/a |
| Purification | Affinity purified by Protein G |
| Storage Buffer | 0.01M PBS, 0.5%BSA, 0.02% Proclin300 |
| Storage Condition | Store at 2-8°C |
| Target | |
| Gene ID | 6693.0 |
| Swiss Prot | P16150 |
| Synonyms | CD 43; CD43 antigen; Galactoglycoprotein; Galactoglycoprotein; GALGP; GPL 115; GPL115; Human gene for sialophorin; Leucocyte sialoglycoprotein; Leucocyte sialoglycoprotein; LEUK_HUMAN; Leukocyte sialoglycoprotein; Leukosialin; LSN; Sialophorin (leukosialin); Sialophorin; SPN. |
| Background | This gene encodes a highly sialylated glycoprotein that functions in antigen-specific activation of T cells, and is found on the surface of thymocytes, T lymphocytes, monocytes, granulocytes, and some B lymphocytes. It contains a mucin-like extracellular domain, a transmembrane region and a carboxy-terminal intracellular region. The extracellular domain has a high proportion of serine and threonine residues, allowing extensive O-glycosylation, and has one potential N-glycosylation site, while the carboxy-terminal region has potential phosphorylation sites that may mediate transduction of activation signals. Different glycoforms of this protein have been described. In stimulated immune cells, proteolytic cleavage of the extracellular domain occurs in some cell types, releasing a soluble extracellular fragment. Defects in expression of this gene are associated with Wiskott-Aldrich syndrome. [provided by RefSeq, Sep 2017] |
| Application Dilution | |
| FCM | 10ul/10^6 cells in 100ul |
Frequently asked questions
Which applications is human CD43/APC (bsm-30036M-APC) validated for, and at what dilution?
bsm-30036M-APC is validated for 10ul/10^6 cells in 100ul.
Which species does human CD43/APC (bsm-30036M-APC) react with?
Tested reactivity: Human.
How should bsm-30036M-APC be stored?
Store at 2-8°C Storage buffer: 0.01M PBS, 0.5%BSA, 0.02% Proclin300