human TDT/PE
Applications
Reactivity
| Overview | |
| Catalog # | bsm-30223m-pe-100t |
| Product Name | human TDT/PE |
| Applications |
FCM
|
| Reactivity | Human |
| Specifications | |
| Conjugation | Unconjugated |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone # | 3H2 |
| Isotype | IgG1/Kappa |
| Concentration | n/a |
| Purification | Affinity purified by Protein G |
| Storage Buffer | 0.01M PBS, 0.5%BSA, 0.02% Proclin300 |
| Storage Condition | Store at 2-8°C |
| Target | |
| Gene ID | 1791.0 |
| Swiss Prot | P04053 |
| Synonyms | Deoxynucleotidyltransferase terminal; DNA nucleotidylexotransferase; TdT; Nucleosidetriphosphate DNA deoxynucleotidylexotransferase; Terminal addition enzyme; Terminal deoxynucleotidyltransferase; Terminal transferase; TDT_HUMAN. |
| Background | This gene is a member of the DNA polymerase type-X family and encodes a template-independent DNA polymerase that catalyzes the addition of deoxynucleotides to the 3'-hydroxyl terminus of oligonucleotide primers. In vivo, the encoded protein is expressed in a restricted population of normal and malignant pre-B and pre-T lymphocytes during early differentiation, where it generates antigen receptor diversity by synthesizing non-germ line elements (N-regions) at the junctions of rearranged Ig heavy chain and T cell receptor gene segments. Alternatively spliced transcript variants encoding different isoforms of this gene have been described. [provided by RefSeq, Jul 2008] |
| Application Dilution | |
| FCM | 10ul/10^6 cells in 100ul |