human/mouse ZAP-70/PE
Applications
Reactivity
| Overview | |
| Catalog # | bsm-30227m-pe-100t |
| Product Name | human/mouse ZAP-70/PE |
| Applications |
FCM
|
| Reactivity | Human |
| Specifications | |
| Conjugation | Unconjugated |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone # | 7D2 |
| Isotype | IgG1 |
| Concentration | n/a |
| Purification | Affinity purified by Protein G |
| Storage Buffer | 0.01M PBS, 0.5%BSA, 0.02% Proclin300 |
| Storage Condition | Store at 2-8°C |
| Target | |
| Gene ID | 7535.0 |
| Swiss Prot | P43403 |
| Synonyms | ZAP-70; ZAP 70; zeta-associated protein 70; ZAP-70=protein tyrosine kinase Syk homolog {SH2-like and C-terminal kinase domains}; Tyrosine-protein kinase ZAP-70; 70 kDa zeta-associated protein; Syk-related tyrosine kinase. SRK; STD; TZK; ZAP70_HUMAN; Tyrosine-protein kinase ZAP-70; 70 kDa zeta-chain associated protein. |
| Background | This gene encodes an enzyme belonging to the protein tyrosine kinase family, and it plays a role in T-cell development and lymphocyte activation. This enzyme, which is phosphorylated on tyrosine residues upon T-cell antigen receptor (TCR) stimulation, functions in the initial step of TCR-mediated signal transduction in combination with the Src family kinases, Lck and Fyn. This enzyme is also essential for thymocyte development. Mutations in this gene cause selective T-cell defect, a severe combined immunodeficiency disease characterized by a selective absence of CD8-positive T-cells. Two transcript variants that encode different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
| Application Dilution | |
| FCM | 10ul/10^6 cells in 100ul |
Frequently asked questions
Which applications is human/mouse ZAP-70/PE (bsm-30227M-PE) validated for, and at what dilution?
bsm-30227M-PE is validated for 10ul/10^6 cells in 100ul.
Which species does human/mouse ZAP-70/PE (bsm-30227M-PE) react with?
Tested reactivity: Human.
How should bsm-30227M-PE be stored?
Store at 2-8°C Storage buffer: 0.01M PBS, 0.5%BSA, 0.02% Proclin300