human IL-10/PE
Applications
Reactivity
| Overview | |
| Catalog # | bsm-30229a-pe-100t |
| Product Name | human IL-10/PE |
| Applications |
FCM
|
| Reactivity | Human |
| Specifications | |
| Conjugation | Unconjugated |
| Host | Rat |
| Clonality | Monoclonal |
| Clone # | 3B4 |
| Isotype | IgG2a/Kappa |
| Concentration | n/a |
| Purification | Affinity purified by Protein G |
| Storage Buffer | 0.01M PBS, 0.5%BSA, 0.02% Proclin300 |
| Storage Condition | Store at 2-8°C |
| Target | |
| Gene ID | 3586.0 |
| Swiss Prot | P22301 |
| Synonyms | Interleukin-10 precursor; Cytokine synthesis inhibitory factor; CSIF; Cytokine Synthesis Inhibitory Factor; IL 10; IL10A; Interleukin 10; Interleukin10; MGC126450; MGC126451; TGIF; IL10_HUMAN. |
| Background | The protein encoded by this gene is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract. Mutations in this gene are associated with an increased susceptibility to HIV-1 infection and rheumatoid arthritis. [provided by RefSeq, May 2020] |
| Application Dilution | |
| FCM | 10ul/10^6 cells in 100ul |
Frequently asked questions
Which applications is human IL-10/PE (bsm-30229A-PE) validated for, and at what dilution?
bsm-30229A-PE is validated for 10ul/10^6 cells in 100ul.
Which species does human IL-10/PE (bsm-30229A-PE) react with?
Tested reactivity: Human.
How should bsm-30229A-PE be stored?
Store at 2-8°C Storage buffer: 0.01M PBS, 0.5%BSA, 0.02% Proclin300