human TNF-α/APC
Applications
Reactivity
| Overview | |
| Catalog # | bsm-30231m-apc-100t |
| Product Name | human TNF-α/APC |
| Applications |
FCM
|
| Reactivity | Human |
| Specifications | |
| Conjugation | Unconjugated |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone # | 6H7 |
| Isotype | IgG1/Kappa |
| Concentration | n/a |
| Purification | Affinity purified by Protein G |
| Storage Buffer | 0.01M PBS, 0.5%BSA, 0.02% Proclin300 |
| Storage Condition | Store at 2-8°C |
| Target | |
| Gene ID | 7124.0 |
| Swiss Prot | P01375 |
| Synonyms | Tumor necrosis factor-α; TNFα; TNF-α; TNFalpha; APC1; Cachectin; DIF; Differentiation inducing factor; Macrophage cytotoxic factor; MCF; Necrosin; TNF a; TNF-alpha; TNF; TNF Macrophage Derived; TNF Monocyte Derived; TNF Superfamily Member 2; TNFA; TNFSF2; Tumor necrosis factor ligand superfamily member 2; Tumor Necrosis Factor Precurso; Tumour Necrosis Factor Alpha; TNFA_HUMAN. |
| Background | This gene encodes a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. This cytokine is mainly secreted by macrophages. It can bind to, and thus functions through its receptors TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. This cytokine is involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. This cytokine has been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, psoriasis, rheumatoid arthritis ankylosing spondylitis, tuberculosis, autosomal dominant polycystic kidney disease, and cancer. Mutations in this gene affect susceptibility to cerebral malaria, septic shock, and Alzheimer disease. Knockout studies in mice also suggested the neuroprotective function of this cytokine. [provided by RefSeq, Aug 2020] |
| Application Dilution | |
| FCM | 10ul/10^6 cells in 100ul |
Frequently asked questions
Which applications is human TNF-α/APC (bsm-30231M-APC) validated for, and at what dilution?
bsm-30231M-APC is validated for 10ul/10^6 cells in 100ul.
Which species does human TNF-α/APC (bsm-30231M-APC) react with?
Tested reactivity: Human.
How should bsm-30231M-APC be stored?
Store at 2-8°C Storage buffer: 0.01M PBS, 0.5%BSA, 0.02% Proclin300