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TTR/Prealbumin Monoclonal Antibody, APC-Cy7 Conjugated

Applications

  • IF(ICC)

Reactivity

  • Human
Overview
Catalog # bsm-33358M-APC-Cy7-100uL
Product Name TTR/Prealbumin Monoclonal Antibody, APC-Cy7 Conjugated
Applications
IF(ICC)
Reactivity Human
Specifications
Conjugation APC-Cy7
Host Mouse
Source Recombinant human TTR Protein
Clonality Monoclonal
Clone # 3E5
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein G.
Storage Buffer Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage Condition Store at -20C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Target
Gene ID 7276
Swiss Prot P02766
Synonyms Transthyretin; Amyloid polyneuropathy; Amyloidosis I; ATTR; Dysprealbuminemic euthyroidal hyperthyroxinemia; Dystransthyretinemic hyperthyroxinemia; HsT2651; PALB; Prealbumin amyloidosis type I; Senile systemic amyloidosis; TBPA; Transthyretin; TTR; TTR protein; prealbumin; TTHY_HUMAN.
Background This gene encodes transthyretin, one of the three prealbumins including alpha-1-antitrypsin, transthyretin and orosomucoid. Transthyretin is a carrier protein; it transports thyroid hormones in the plasma and cerebrospinal fluid, and also transports retinol (vitamin A) in the plasma. The protein consists of a tetramer of identical subunits. More than 80 different mutations in this gene have been reported; most mutations are related to amyloid deposition, affecting predominantly peripheral nerve and/or the heart, and a small portion of the gene mutations is non-amyloidogenic. The diseases caused by mutations include amyloidotic polyneuropathy, euthyroid hyperthyroxinaemia, amyloidotic vitreous opacities, cardiomyopathy, oculoleptomeningeal amyloidosis, meningocerebrovascular amyloidosis, carpal tunnel syndrome, etc. [provided by RefSeq]
Application Dilution
IF(ICC) 1:50-200

Frequently asked questions

Which applications is TTR/Prealbumin Monoclonal Antibody, APC-Cy7 Conjugated (bsm-33358M-APC-Cy7) validated for, and at what dilution?

bsm-33358M-APC-Cy7 is validated for IF(ICC) (1:50-200). These are recommended starting dilutions; optimal dilutions should be determined by the end user.

Which species does TTR/Prealbumin Monoclonal Antibody, APC-Cy7 Conjugated (bsm-33358M-APC-Cy7) react with?

Tested reactivity: Human.

How should bsm-33358M-APC-Cy7 be stored?

Store at -20C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. Storage buffer: Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

What immunogen was used to raise TTR/Prealbumin Monoclonal Antibody, APC-Cy7 Conjugated (bsm-33358M-APC-Cy7)?

Recombinant human TTR Protein

What are the excitation and emission wavelengths of the APC-Cy7 conjugate (bsm-33358M-APC-Cy7)?

APC-Cy7 on bsm-33358M-APC-Cy7: excitation / emission 650nm/780nm.