| Overview |
| bsm-33376m-pe-100ul |
| HP1 gamma Monoclonal Antibody, PE Conjugated |
| WB, IF |
| Human, Mouse, Rat |
| Specifications |
| PE |
| Mouse |
| Recombinant human HP1 gamma Protein |
| Monoclonal |
| 6F4 |
| IgG |
| 1ug/ul |
| Purified by Protein A. |
| Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target |
| 11335 |
| Q13185 |
| CBX 3; CBX3; Chromobox homolog 3; Chromobox protein homolog 3; HECH; Heterochromatin like protein 1; Heterochromatin protein 1 homolog gamma; Heterochromatin protein HP1 gamma; HP1 gamma homolog; HP1Hs gamma ; Modifier 2; protein HP1-GAMMA; HP1g; M32; MGC118084; CBX3_HUMAN; Modifier 2 protein; HP-1-γ; HP 1γ; HP-1γ; HP-1 γ; HP1γ; HP1 γ; |
| HP1 gamma appears to be involved in transcriptional silencing in heterochromatin-like complexes. It recognizes and binds histone H3 tails methylated at 'Lys-9', leading to epigenetic repression. HP1 gamma may contribute to the association of the heterochromatin with the inner nuclear membrane through its interaction with lamin B receptor (LBR) and involved in the formation of functional kinetochore through interaction with MIS12 complex proteins. |
| Application Dilution |
| WB |
1:100-500 |
| IF |
|
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