HP1 alpha Monoclonal Antibody, AbBy Fluor-350 Conjugated
Applications
Reactivity
| Overview | |
| Catalog # | bsm-33377m-bf350-100uL |
| Product Name | HP1 alpha Monoclonal Antibody, AbBy Fluor-350 Conjugated |
| Applications |
WB
IF
|
| Reactivity | Human, Mouse, Rat |
| Specifications | |
| Conjugation | AbBy Fluor-350 |
| Host | Mouse |
| Source | KLH conjugated synthetic peptide derived from human HP1 alpha |
| Clonality | Monoclonal |
| Clone # | 7.00E+03 |
| Isotype | IgG |
| Concentration | 1ug/ul |
| Purification | Purified by Protein A. |
| Storage Buffer | Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target | |
| Gene ID | 23468 |
| Swiss Prot | P45973 |
| Synonyms | Antigen p25; HP1-_; CBX5; CBX5_HUMAN; Chromobox homolog 5 (HP1 alpha homolog, Drosophila); Chromobox homolog 5; Chromobox protein homolog 5; Heterochromatin protein 1 alpha; Heterochromatin protein 1; Heterochromatin protein 1 homolog alpha; HP1 alpha; HP1 alpha homolog; HP1; HP1A; HP1Hs alpha. |
| Background | Component of heterochromatin that recognizes and binds histone H3 tails methylated at 'Lys-9' (H3K9me), leading to epigenetic repression. In contrast, it is excluded from chromatin when 'Tyr-41' of histone H3 is phosphorylated (H3Y41ph). Can interact with lamin-B receptor (LBR). This interaction can contribute to the association of the heterochromatin with the inner nuclear membrane. Involved in the formation of functional kinetochore through interaction with MIS12 complex proteins. |
| Application Dilution | |
| WB | 1:300-5000 |
| IF | |
Frequently asked questions
Which applications is HP1 alpha Monoclonal Antibody, AbBy Fluor-350 Conjugated (bsm-33377M-BF350) validated for, and at what dilution?
bsm-33377M-BF350 is validated for WB (1:300-5000); IF. These are recommended starting dilutions; optimal dilutions should be determined by the end user.
Which species does HP1 alpha Monoclonal Antibody, AbBy Fluor-350 Conjugated (bsm-33377M-BF350) react with?
Tested reactivity: Human, Mouse, Rat.
How should bsm-33377M-BF350 be stored?
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. Storage buffer: Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
What immunogen was used to raise HP1 alpha Monoclonal Antibody, AbBy Fluor-350 Conjugated (bsm-33377M-BF350)?
KLH conjugated synthetic peptide derived from human HP1 alpha
What are the excitation and emission wavelengths of the AbBy Fluor-350 conjugate (bsm-33377M-BF350)?
AbBy Fluor-350 on bsm-33377M-BF350: excitation / emission 346nm/442nm.