SARS-CoV-2 Nucleocapsid Protein Monoclonal Antibody (14B2D)

Applications

  • WB
  • ELISA
  • IHC-P

Reactivity

  • Virus
Overview
Catalog # bsm-41415M
Product Name SARS-CoV-2 Nucleocapsid Protein Monoclonal Antibody (14B2D)
Applications WB, ELISA, IHC-P
Reactivity Virus
Specifications
Conjugation Unconjugated
Host Mouse
Clonality Monoclonal
Clone # 14B2D
Isotype IgG2b
Concentration 1ug/ul
Purification Purified by Protein G.
Storage Buffer Aqueous buffered solution containing 0.01M PBS(pH7.4) with 0.1% Proclin300.
Storage Condition Store at -20°C for 12 months.
Target
Swiss Prot P0DTC9
Synonyms SARS-CoV-2 Nucleocapsid Protein; SARS-CoV-2 NP; nucleocapsid protein [Severe acute respiratory syndrome coronavirus 2]; novel coronavirus N Protein; novel coronavirus Nucleocapsid Protein; 2019-nCoV Nucleoprotein; 2019-nCoV N; 2019nCoV N; 2019-nCoV N Protein; 2019 peak N Protein; 2019-nCoV nucleocapsid protein.
Background Coronaviruses are enveloped viruses with a positive-sense RNA genome and with a nucleocapsid of helical symmetry. Coronavirus nucleoproteins localize to the cytoplasm and the nucleolus, a subnuclear structure, in both virus-infected primary cells and in cells transfected with plasmids that express N protein. Coronavirus N protein is required for coronavirus RNA synthesis, and has RNA chaperone activity that may be involved in template switch. Nucleocapsid protein is a most abundant protein of coronavirus. During virion assembly, N protein binds to viral RNA and leads to formation of the helical nucleocapsid. Nucleocapsid protein is a highly immunogenic phosphoprotein also implicated in viral genome replication and in modulating cell signaling pathways. Because of the conservation of N protein sequence and its strong immunogenicity, the N protein of coronavirus is chosen as a diagnostic tool.
Application Dilution
WB 1:300-1000
ELISA 1:500-1000
IHC-P 1:200-400