MMP14 (3A6) Monoclonal Antibody
Applications
Reactivity
| Overview | |
| Catalog # | bsm-51028M-100uL |
| Product Name | MMP14 (3A6) Monoclonal Antibody |
| Applications |
WB
IHC-F
IF
IHC-P
|
| Reactivity | Human |
| Specifications | |
| Conjugation | Unconjugated |
| Host | Mouse |
| Source | This MMP14 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 470-499 amino acids from the C-terminal region of human MMP14. |
| Clonality | Monoclonal |
| Clone # | 3A6 |
| Isotype | IgG |
| Concentration | Lot Dependent |
| Purification | Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purifie |
| Storage Buffer | 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles. |
| Target | |
| Gene ID | 4323 |
| Swiss Prot | P50281 |
| Synonyms | MMP-14; MMP-X1; MT-MMP; MT1MMP; MTMMP1; WNCHRS; MT1-MMP; MT-MMP 1; Matrix metalloproteinase-14; Membrane-type matrix metalloproteinase 1; Membrane-type-1 matrix metalloproteinase; MMP14 |
| Background | Seems to specifically activate progelatinase A. May thus trigger invasion by tumor cells by activating progelatinase A on the tumor cell surface. May be involved in actin cytoskeleton reorganization by cleaving PTK7. Acts as a positive regulator of cell growth and migration via activation of MMP15. Involved in the formation of the fibrovascular tissues in association with pro-MMP2. |
| Application Dilution | |
| WB | 1:300-5000 |
| IHC-F | 1:100-500 |
| IF | 1:50-200 |
| IHC-P | 1:200-400 |
Frequently asked questions
Which applications is MMP14 (3A6) Monoclonal Antibody (bsm-51028M) validated for, and at what dilution?
bsm-51028M is validated for WB (1:300-5000); IHC-F (1:100-500); IF (1:50-200); IHC-P (1:200-400). These are recommended starting dilutions; optimal dilutions should be determined by the end user.
Which species does MMP14 (3A6) Monoclonal Antibody (bsm-51028M) react with?
Tested reactivity: Human.
How should bsm-51028M be stored?
Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles. Storage buffer: 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
What immunogen was used to raise MMP14 (3A6) Monoclonal Antibody (bsm-51028M)?
This MMP14 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 470-499 amino acids from the C-terminal region of human MMP14.