PRKAA2 (6C2) Monoclonal Antibody
Applications
Reactivity
| Overview | |
| Catalog # | bsm-51055M-100uL |
| Product Name | PRKAA2 (6C2) Monoclonal Antibody |
| Applications |
WB
IF
|
| Reactivity | Human |
| Specifications | |
| Conjugation | Unconjugated |
| Host | Mouse |
| Source | This PRKAA2 monoclonal antibody is generated from mouse immunized with PRKAA2 recombinant protein. |
| Clonality | Monoclonal |
| Clone # | 6C2 |
| Isotype | IgG2a |
| Concentration | Lot Dependent |
| Purification | Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purifie |
| Storage Buffer | 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Store at -20°C for 12 months. |
| Target | |
| Gene ID | 5563 |
| Swiss Prot | P54646 |
| Synonyms | AMPK; AMPK2; PRKAA; AMPKa2; 5'-AMP-activated protein kinase catalytic subunit alpha-2; AMPK subunit alpha-2; Acetyl-CoA carboxylase kinase; ACACA kinase; Hydroxymethylglutaryl-CoA reductase kinase; HMGCR kinase; PRKAA2 |
| Background | The protein encoded by this gene is a catalytic subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. Studies of the mouse counterpart suggest that this catalytic subunit may control whole-body insulin sensitivity and is necessary for maintaining myocardial energy homeostasis during ischemia. |
| Application Dilution | |
| WB | 1:300-5000 |
| IF | 1:50-200 |
Frequently asked questions
Which applications is PRKAA2 (6C2) Monoclonal Antibody (bsm-51055M) validated for, and at what dilution?
bsm-51055M is validated for WB (1:300-5000); IF (1:50-200). These are recommended starting dilutions; optimal dilutions should be determined by the end user.
Which species does PRKAA2 (6C2) Monoclonal Antibody (bsm-51055M) react with?
Tested reactivity: Human.
How should bsm-51055M be stored?
Store at -20°C for 12 months. Storage buffer: 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
What immunogen was used to raise PRKAA2 (6C2) Monoclonal Antibody (bsm-51055M)?
This PRKAA2 monoclonal antibody is generated from mouse immunized with PRKAA2 recombinant protein.