MAP3K11 (3T1) Monoclonal Antibody
Applications
Reactivity
| Overview | |
| Catalog # | bsm-51068M |
| Product Name | MAP3K11 (3T1) Monoclonal Antibody |
| Applications |
WB
|
| Reactivity | Human |
| Specifications | |
| Conjugation | Unconjugated |
| Host | Mouse |
| Source | This MAP3K11 monoclonal antibody is generated from mouse immunized with MAP3K11 recombinant protein. |
| Clonality | Monoclonal |
| Clone # | 3T1 |
| Isotype | IgM |
| Concentration | 0.5ug/ul |
| Purification | Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide. |
| Storage Buffer | 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Store at -20°C for 12 months. |
| Target | |
| Gene ID | 4296 |
| Swiss Prot | Q16584 |
| Synonyms | MLK3; PTK1; SPRK; MLK-3; MEKK11; Mitogen-activated protein kinase kinase kinase 11; Mixed lineage kinase 3; Src-homology 3 domain-containing proline-rich kinase; MAP3K11 |
| Background | Activates the JUN N-terminal pathway. Required for serum-stimulated cell proliferation and for mitogen and cytokine activation of MAPK14 (p38), MAPK3 (ERK) and MAPK8 (JNK1) through phosphorylation and activation of MAP2K4/MKK4 and MAP2K7/MKK7. Plays a role in mitogen-stimulated phosphorylation and activation of BRAF, but does not phosphorylate BRAF directly. Influences microtubule organization during the cell cycle. |
| Application Dilution | |
| WB | 1:300-5000 |