Free Shipping On Orders Over $1,000!

SRC (17AT28) Monoclonal Antibody

Applications

  • WB

Reactivity

  • Human
  • Mouse
Overview
Catalog # bsm-51271M
Product Name SRC (17AT28) Monoclonal Antibody
Applications WB
Reactivity Human, Mouse
Specifications
Conjugation Unconjugated
Host Mouse
Source This Src antibody is generated from mouse immunized with a recombinant protein of full length human SRC.
Clonality Monoclonal
Clone # 17AT28
Isotype IgG1
Concentration 0.5ug/ul
Purification Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage Condition Store at -20°C for 12 months.
Target
Gene ID 6714
Swiss Prot P12931
Synonyms ASV; SRC1; THC6; c-SRC; p60-Src; Proto-oncogene tyrosine-protein kinase Src; Proto-oncogene c-Src; pp60c-src; SRC
Background This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. Two transcript variants encoding the same protein have been found for this gene.
Application Dilution
WB 1:300-5000