| Overview |
| bsm-51337M |
| MCM3 (3C3) Monoclonal Antibody |
| WB, FCM |
| Human, Mouse, Rat |
| Specifications |
| Unconjugated |
| Mouse |
| This MCM3 antibody is generated from a mouse immunized with a recombinant protein of human MCM3. |
| Monoclonal |
| 3C3 |
| IgG1 |
| 0.5ug/ul |
| Purified by Protein G. |
| 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Store at -20°C for 12 months. |
| Target |
| 4172 |
| P25205 |
| HCC5; P1.h; RLFB; P1-MCM3; DNA replication licensing factor MCM3; DNA polymerase alpha holoenzyme-associated protein P1; RLF subunit beta; p102; MCM3 |
| Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity. Required for DNA replication and cell proliferation. |
| Application Dilution |
| WB |
1:300-5000 |
| FCM |
1:20-100 |
Powered by Bioz