Overview |
bsm-51349M |
BANP (4C2) Monoclonal Antibody |
WB, IHC-P |
Human |
Specifications |
Unconjugated |
Mouse |
This BANP antibody is generated from a mouse immunized with a recombinant protein between 30-390 amino acids from human BANP. |
Monoclonal |
4C2 |
IgG1 |
0.5ug/ul |
Purified by Protein G. |
0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
Store at -20°C for 12 months. |
Target |
54971 |
Q8N9N5 |
BEND1; SMAR1; SMARBP1; Protein BANP; BEN domain-containing protein 1; Btg3-associated nuclear protein; Scaffold/matrix-associated region-1-binding protein; BANP |
Controls V(D)J recombination during T-cell development by repressing T-cell receptor (TCR) beta enhancer function. Binds to scaffold/matrix attachment region beta (S/MARbeta), an ATC-rich DNA sequence located upstream of the TCR beta enhancer. Represses cyclin D1 transcription by recruiting HDAC1 to its promoter, thereby diminishing H3K9ac, H3S10ph and H4K8ac levels. Promotes TP53 'Ser-15' phosphorylation and nuclear accumulation, which causes cell cycle arrest (By similarity). |
Application Dilution |
WB |
1:300-5000 |
IHC-P |
1:200-400 |