USP14 (9C1) Monoclonal Antibody
Applications
Reactivity
| Overview | |
| Catalog # | bsm-51409M |
| Product Name | USP14 (9C1) Monoclonal Antibody |
| Applications |
WB
|
| Reactivity | Human, Mouse, Rat |
| Specifications | |
| Conjugation | Unconjugated |
| Host | Mouse |
| Source | Purified His-tagged USP14 protein was used to produced this monoclonal antibody. |
| Clonality | Monoclonal |
| Clone # | 9C1 |
| Isotype | IgG1 |
| Concentration | Lot Dependent |
| Purification | Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purifie |
| Storage Buffer | 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Store at -20°C for 12 months. |
| Target | |
| Gene ID | 9097 |
| Swiss Prot | P54578 |
| Synonyms | TGT; Ubiquitin carboxyl-terminal hydrolase 14; Deubiquitinating enzyme 14; Ubiquitin thioesterase 14; Ubiquitin-specific-processing protease 14; USP14 |
| Background | Proteasome-associated deubiquitinase which releases ubiquitin from the proteasome targeted ubiquitinated proteins. Ensures the regeneration of ubiquitin at the proteasome. Is a reversibly associated subunit of the proteasome and a large fraction of proteasome-free protein exists within the cell. Required for the degradation of the chemokine receptor CXCR4 which is critical for CXCL12-induced cell chemotaxis. Serves also as a physiological inhibitor of endoplasmic reticulum-associated degradation (ERAD) under the non-stressed condition by inhibiting the degradation of unfolded endoplasmic reticulum proteins via interaction with ERN1. Indispensable for synaptic development and function at neuromuscular junctions (NMJs). |
| Application Dilution | |
| WB | 1:300-5000 |
Frequently asked questions
Which applications is USP14 (9C1) Monoclonal Antibody (bsm-51409M) validated for, and at what dilution?
bsm-51409M is validated for WB (1:300-5000). These are recommended starting dilutions; optimal dilutions should be determined by the end user.
Which species does USP14 (9C1) Monoclonal Antibody (bsm-51409M) react with?
Tested reactivity: Human, Mouse, Rat.
How should bsm-51409M be stored?
Store at -20°C for 12 months. Storage buffer: 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
What immunogen was used to raise USP14 (9C1) Monoclonal Antibody (bsm-51409M)?
Purified His-tagged USP14 protein was used to produced this monoclonal antibody.