RYK Monoclonal Antibody

$Lane 1: U251 cell lysates probed with RYK Monoclonal Antibody, Unconjugated (bsm-51489M) at 1:1000 dilution and 4\u00b0C overnight incubation. Followed by conjugated secondary antibody incubation at 1:20000 for 60 min at 37˚C.$

Lane 1: U251 cell lysates probed with RYK Monoclonal Antibody, Unconjugated (bsm-51489M) at 1:1000 dilution and 4\u00b0C overnight incubation. Followed by conjugated secondary antibody incubation at 1:20000 for 60 min at 37˚C.

Applications

Predicted Reactivity

Human

Overview
Catalog #	bsm-51489M
Product Name	RYK Monoclonal Antibody
Applications	WB
Predicted Reactivity	Human
Specifications
Conjugation	Unconjugated
Host	Mouse
Source	Recombinant human RYK.
Clonality	Monoclonal
Clone #	F12G6
Concentration	0.5ug/ul
Storage Buffer	0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage Condition	Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
Target
Gene ID	6259
Swiss Prot	P34925
Subcellular location	Nucleus
Synonyms	D3S3195; ERK 3; Hydroxyaryl protein kinase; JTK 5; JTK 5A; JTK5; JTK5A; JTK5A protein tyrosine kinase; receptor like tyrosine kinase; receptor like tyrosine kinase precursor; RYK 1; RYK_HUMAN; RYK1; Tyrosine protein kinase RYK; Tyrosine protein kinase RYK precursor; Tyrosine-protein kinase RYK; Vik;
Background	May be a coreceptor along with FZD8 of Wnt proteins, such as WNT1, WNT3, WNT3A and WNT5A. Involved in neuron differentiation, axon guidance, corpus callosum establishment and neurite outgrowth. In response to WNT3 stimulation, receptor C-terminal cleavage occurs in its transmembrane region and allows the C-terminal intracellular product to translocate from the cytoplasm to the nucleus where it plays a crucial role in neuronal development.
Application Dilution
WB	=1:500-2000Ôºå

Applications

Predicted Reactivity

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